Medical Animation and Communication

Diabetes is a condition of elevated glucose levels in the blood. A blood glucose level of 72-99 mg/dL after overnight fasting is considered as normal, a glucose level between 100-125 mg/dL is a sign of prediabetes and a glucose level >125 mg/dL is a sign of diabetes. Read More

Gout is a type of arthritis which develops when a high level of uric acid deposits in the body and forms needle-like crystals in the joints and therefore, causes swelling and severe pain in the joints, often the joint at the base of the big toe. Gout occurs mostly in men between the ages of 30 to 50 years, in women after the menopause, and in patients with kidney disease.Read More 

Allergic rhinitis or hay fever is a disease in which a person rapidly develops cold-like symptoms after coming in contact with certain substances (allergens). The symptoms occur because the body’s immune system reacts against an allergic substance(s). Read More

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Rheumatoid arthritis is a chronic inflammatory autoimmune disease in which the immune system mistakenly attacks the healthy cells in the body, which leads to inflammation. It primarily affects joints mainly in the wrist, hands, and feet and causes pain, swelling, stiffness, and over time can cause joint damage or loss of joint function Read More 

Irritable bowel syndrome (IBS) is a digestive system disorder in which a person experiences multiple symptoms that impacts his/her daily life. Irritable bowel syndrome affects 10-15% of the population around the world, but the exact cause of IBS is unknown. The occurrence of IBS is higher in women than in men.Read More 

Pain is an unpleasant sensual signal arises in the brain due to tissue damage. Nowadays, pain is a very common problem which hampers the work, sleep, activities and also spoils the quality of time with family and friends. Therefore, pain management is necessary to provide relief and improve quality of life. However, pain can only be managed once it is known which type of pain the person has. Read More 

Skin is an essential part of the human body. It protects the body from various environmental hazards. Skin diseases are common as this is the largest organ among the integumentary system’s organs in the human body. Dermatology deals with the skin and skin related appendages (hair, nails, etc.) and skin diseases. A doctor who deals with skin diseases is known as a dermatologist. Read More 

Medical animation is an instructional or training tool used by the wide audience such as healthcare professionals, patients, students, etc. It is prepared as a short educational film or video that explains the health topics and complex medical processes more easily and effectively such as the origin of the disease, how a drug works in the body and improves the symptoms.Read More 

Statistics is a fundamental aspect of clinical trials. Statistical concepts are used at every stage of a clinical trial, i.e., in protocol development and design, conduct and data monitoring, data analyses, data management and reporting of results. Statistical analysis enables the researchers to make accurate interpretations from the collected data. Some of the key concepts of statistics that help in the demonstration of accurate results include. Read More

Anti-infectives are the agents or drugs that help to eradicate the infection from the human body. Some of the anti-infectives do this by inhibiting the action of the infectious agent (bacteria, viruses, fungi, etc.) and some by killing the infectious agent itself. As the infectious diseases like dengue fever, Ebola infection, tuberculosis, bacterial meningitis, malaria, etc., are rising at a high pace, the development of new anti-infective agents has become a global health priority.Read More

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Clinical trials are studies conducted to test the pharmacokinetics, pharmacodynamics, safety and efficacy of a drug. A lot of resources are utilized to conduct the study across multiple clinical sites. These sites produce the safety and efficacy data which are then submitted to a regulator for getting approval. The regulator reviews this data and awards the sponsor with drug approval if the data are found to be adequate. The data provided to the regulator must be quality data (i.e., consistent, reliable and related to the drug) to achieve drug approval. If inconsistent and incomplete data are submitted to the regulators, the regulators will raise the number of queries and will not provide the approval to the drug. That is why monitoring practices are essential to ensure data quality. Traditionally, source data verification is often used by sponsors to manage the quality of trial data. However, recent studies prove that source data verification cannot ensure the quality of data. An addendum ICH-E6-R2 to this original document ICH-E6-R1 has been published on 1st March 2018 which has implemented a number of changes throughout the document. There is also a new info for the use of a statistical approach which has defined the role of statistics in improving the quality of data in a clinical study. Addendum ICH-E6-R2 favors the Centralized Monitoring that helps in differentiating reliable and potentially unreliable data. To enhance the data quality in clinical trials, there is another combination approach, i.e., Centralized Statistical Monitoring which is a combination of Centralized Monitoring and Statistical Monitoring. . By utilizing Centralized Statistical Monitoring to analyze the clinical trial data, quality data can be generated.

Alzheimer’s disease (AD) is a brain disorder that slowly destroys memory and thinking abilities. It generally appears older population (during the mid-60s). In the United States, it is estimated that >5 million people are affected by AD. The commonly reported early symptoms are memory loss, unpredictable behavior, language problems, confusion, etc. Read More

Clinical trials are the investigations involving people to test new treatments, tests or inventions as a means to detect, prevent, treat, or accomplish various medical conditions. It helps to determine whether a new invention works, is it safe, and if it is better than already available treatments. It involves both, the healthy individuals and the patients. There are four phases of clinical trials:

Phase I include few individuals (e.g. 20-80) to test safety and possible side effects.

Phase II include few hundreds of people to determine efficacy and evaluate further safety.

Phase III usually involve thousands of people to check safety, level of effectiveness and side effects.

Phase IV involves FDA approval, once a drug is approved by FDA and made available to the public, investigators continue to study its safety, to understand the best use of the new treatment. Information is gathered from population on drug’s long term effectiveness and adverse side effects.